http://www.cancerindex.org/geneweb/TERF2.htm Web29 Mar 2002 · TRF2 accelerated telomere shortening in several fibroblast strains, regardless of the status of p53 or the p16-RB pathways. Inhibition of p53 with the p53-175H dominant negative allele or suppression of both the p53 and RB pathways with viral oncoproteins (SV40 large T or HPV16-E6 and -E7) did not change the rate of telomere shortening, nor …
The Telomeric Protein TRF2 Regulates Angiogenesis by Binding …
Web5 Dec 2024 · To determine the significance of TRF2 recruitment to damage sites, the effects of TRF2 depletion were examined using cell-based assays for different pathways of DSB repair (Hu and Parvin, 2014). TRF2 was depleted for 48 h before repair assays in order to minimize telomere erosion, which was typically assayed 4–7 days after depletion ( … WebTRF1-interacting nuclear protein 2 (TIN2), encoded by the TERF1-interacting nuclear factor 2 (TINF2) gene, is part of the shelterin complex and interacts with the shelterin factors TRF1, TRF2, and TPP1. Mutations in TINF2 cause DC and more rarely HH. So far, most of the mutations identified are de novo (and consequently autosomal dominant) and ... gyms near tucker ga
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WebTRF2 is a specific target of miR-23a, and uncover a previously unknown role for miR-23a in telomere regulation and cellular senescence. The variability of genes encoding for TERF1 … WebProtein Recombinant Human TRF2 protein (ab152737) View more associated products Overview Product name Anti-TRF2 antibody [4A794] See all TRF2 primary antibodies Description Mouse monoclonal [4A794] to TRF2 Host species Mouse Tested applications Suitable for: IHC-P, WB, Flow Cyt (Intra) more details Species reactivity Reacts with: … WebRequires Internet Explorer 8 or above: Forgot your password? Call 1-800-977-8943 Copyright© 2024 Sedgwick Privacy Policy Terms & Conditions Privacy Policy gyms near tysons corner